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Acta Pharmaceutica Sinica ; (12): 1258-1261, 2009.
Article in English | WPRIM | ID: wpr-344098

ABSTRACT

Two erythrodiol triterpene fatty esters, 3beta-dodecanoyl erythrodiol (1) and 3beta-tetradecanoyl erythrodiol (2), were isolated from Scorzonera mongolica. Their structures were elucidated on the basis of IR, MS and extensive 2D NMR spectroscopic analysis. Compound 1 was identified to be a new compound and 2 was confirmed to be a new natural compound. Their antitumor effects in vitro were evaluated with MTT and SRB assays, but compounds 1 and 2 only showed moderate cytotoxicities on A-549 cell line.


Subject(s)
Animals , Humans , Mice , Antineoplastic Agents, Phytogenic , Chemistry , Pharmacology , Carcinoma, Hepatocellular , Pathology , Cell Line, Tumor , Drugs, Chinese Herbal , Chemistry , Pharmacology , Leukemia P388 , Pathology , Liver Neoplasms , Pathology , Lung Neoplasms , Pathology , Magnetic Resonance Spectroscopy , Molecular Structure , Plants, Medicinal , Chemistry , Scorzonera , Chemistry , Triterpenes , Chemistry , Pharmacology
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